Pharmaceutical fermentation isobutanol waste gas, suitable for membrane condensation

Pharmaceutical fermentation isobutanol waste gas, suitable for membrane condensation

In pharmaceutical fermentation processes, isobutanol is often volatilized into the exhaust system as a metabolite or solvent. Isobutanol has a boiling point of 108 degrees Celsius and is a medium boiling point alcohol solvent. It is partially miscible with water and has typical hydrophilic properties of alcohols. If this kind of waste gas is discharged directly, it will not only cause waste of solvent, but also bring odor and environmental protection problems.

The membrane condensation recovery process is suitable for the treatment of isobutanol waste gas. The core process is that the exhaust gas first enters the three-stage condensing unit, and the temperature is gradually reduced to minus five to minus fifteen degrees Celsius. In this temperature range, the saturated vapor pressure of isobutanol is significantly reduced, and most of it is liquefied from the gaseous state to the liquid state and recovered from the bottom of the equipment. The choice of condensation temperature is the key. The boiling point of isobutanol is higher than that of n-butanol, and the condensation difficulty is relatively low. A higher recovery rate can be achieved at about minus ten degrees. The small amount of uncondensed tail gas then passes throughgas separation membraneThe membrane enriches the residual isobutanol and circulates it back to the condensation inlet for further treatment.

In terms of membrane material selection, studies have shown that high-performance ZIF-8 composite membranes can efficiently enrich isobutanol from low-concentration fermentation broth, with a separation factor of thirty-four to forty and excellent permeability. This kind of membrane has preferential permeability to alcohol macromolecules, can effectively intercept water molecules, and is particularly suitable for the recovery scenario of alcohol waste gas.

Fermentation off-gases typically carry high humidity, which can affect condensation efficiency and recovered solvent quality. To solve this problem, a pre-dehumidification device can be added before the condensation unit, or a gas-liquid separator can be installed in the three-stage condensation to effectively separate the condensed water from isobutanol. Because isobutanol is partially miscible with water, the recovered solvent will contain a small amount of water, and isobutanol with low water content can be obtained after standing and layering, which can be directly reused in the production process that is not sensitive to moisture. For scenarios requiring high purity, a molecular sieve drying unit can be added at the back end for further dehydration.

Pharmaceutical fermentation isobutanol exhaust gas usually has small air volume and medium concentration, which is very suitable for the configuration of skid-mounted membrane condensation unit. The equipment adopts integrated design, occupies a small area, and can be directly connected with the exhaust pipe of the fermentation tank. Explosion-proof configuration is suitable for pharmaceutical explosion-proof places, PLC automatic control, stable operation.

LuoyangWohong PetrochemicalEquipment Co., Ltd. provides membrane condensation recovery scheme for pharmaceutical fermentation isobutanol waste gas, and the equipment can be customized according to the air volume and concentration of the waste gas. The company is located at W2-1, Dongda Science and Technology Industrial Park, Luoxin Industrial Cluster Zone, Xin’an County, Luoyang City. Website: www.wohongshihua.com.